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Very frequent, regretfully, is diabetes mellitus in children, which is due to exhaustion of pancreas. In children, it is insulin-dependent and Insulin is applied in all cases, except in teenagers with overweight. We always look for family medical history, but recently there are frequent cases when the child suffers without any hereditary reasons. The main symptoms of diabetes mellitus is drinking of much water and night emiction, increased appetite, loss of weight, dry skin and mucosa, acetone smell. At the least doubt for this lesion, it very important to test the blood sugar to avoid ketoacidosis coma of children with loss of conscious and severe metabolic changes, if diagnosis is delayed.